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tsoledronihappo, noun
Word analysis
tsoledronihappo

tsoledronihappo

tsoledronihappo

Noun, Singular Nominative
Report an issue

Declensions

Singular

Plural

Nom

-

tsoledronihappo

tsoledronihapot

Par

-ta

tsoledronihappoa

tsoledronihappoja

Gen

-n

tsoledronihapon

tsoledronihappojen

Ill

mihin

tsoledronihappoon

tsoledronihappoihin

Ine

-ssa

tsoledronihapossa

tsoledronihapoissa

Ela

-sta

tsoledronihaposta

tsoledronihapoista

All

-lle

tsoledronihapolle

tsoledronihapoille

Ade

-lla

tsoledronihapolla

tsoledronihapoilla

Abl

-lta

tsoledronihapolta

tsoledronihapoilta

Tra

-ksi

tsoledronihapoksi

tsoledronihapoiksi

Ess

-na

tsoledronihappona

tsoledronihappoina

Abe

-tta

tsoledronihapotta

tsoledronihapoitta

Com

-ne

-

tsoledronihappoine

Ins

-in

-

tsoledronihapoin

Declensions

Singular

Plural

Nom

-

tsoledronihappo

tsoledronihapot

Par

-ta

tsoledronihappoa

tsoledronihappoja

Gen

-n

tsoledronihapon

tsoledronihappojen

Ill

mihin

tsoledronihappoon

tsoledronihappoihin

Ine

-ssa

tsoledronihapossa

tsoledronihapoissa

Ela

-sta

tsoledronihaposta

tsoledronihapoista

All

-lle

tsoledronihapolle

tsoledronihapoille

Ade

-lla

tsoledronihapolla

tsoledronihapoilla

Abl

-lta

tsoledronihapolta

tsoledronihapoilta

Tra

-ksi

tsoledronihapoksi

tsoledronihapoiksi

Ess

-na

tsoledronihappona

tsoledronihappoina

Abe

-tta

tsoledronihapotta

tsoledronihapoitta

Com

-ne

-

tsoledronihappoine

Ins

-in

-

tsoledronihapoin
zoledronic acid
zoledonic acid
Show more arrow right EMEA0.3; eurlex-diff-2018-06-20; EurLex-2 Tsoledronihappo eliminoituu erittymällä munuaisten kautta. Zoledronic acid is eliminated by renal excretion. Pullo sisältää mg vedetöntä tsoledronihappoa. Bottle contains # mg zoledronic acid (anhydrous. Vaikutusmekanismi Typpeä sisältäviin bisfosfonaatteihin kuuluva tsoledronihappo vaikuttaa ensisijaisesti luuhun. Mechanism of action Zoledronic acid belongs to the class of nitrogen-containing bisphosphonates and acts primarily on bone. Subkrooninen ja krooninen toksisuus Tsoledronihappo oli hyvin siedetty, kun sitä annettiin rotalle ihon alle ja koiralle laskimoon enimmillään, mg kg vuorokaudessa neljän viikon ajan. Subchronic and chronic toxicity Zoledronic acid was well tolerated when administered subcutaneously to rats and intravenously to dogs at doses up to # mg/kg daily for # weeks. Tsoledronihappo ei sitoudu mainittavassa määrin plasman proteiineihin eikä estä ihmisen Pns-entsyymejä in vitro (ks. kohta.), mutta muodollisia kliinisiä interaktiotutkimuksia ei ole tehty. Zoledronic acid shows no appreciable binding to plasma proteins and does not inhibit human P# enzymes in vitro (see section #), but no formal clinical interaction studies have been performed. Mutageenisuus ja karsinogeenisuus Mutageenisuuskokeiden perusteella tsoledronihappo ei ollut mutageeninen eivätkä karsinogeenisuustutkimukset viitanneet siihen, että tsoledronihappo olisi karsinogeeninen. Mutagenicity and carcinogenic potential Zoledronic acid was not mutagenic in the mutagenicity tests performed and carcinogenicity testing did not provide any evidence of carcinogenic potential. Mutageenisuus ja karsinogeenisuus Mutageenisuuskokeiden perusteella tsoledronihappo ei ollut mutageeninen, eivätkä karsinogeenisuustutkimukset viitanneet siihen, että tsoledronihappo olisi karsinogeeninen. Mutagenicity and carcinogenic potential Zoledronic acid was not mutagenic in the mutagenicity tests performed and carcinogenicity testing did not provide any evidence of carcinogenic potential. Sen lisäksi, että tsoledronihappo on potentti luun resorption estäjä, sillä on myös useita kasvainten kasvua estäviä ominaisuuksia, jotka saattavat myötävaikuttaa sen tehoon metastaattisen luusairauden hoidossa. In addition to being a potent inhibitor of bone resorption, zoledronic acid also possesses several anti-tumour properties that could contribute to its overall efficacy in the treatment of metastatic bone disease. Novartisille myönnettiin keskitetyssä lupamenettelyssä myyntilupa lääkkeelle nimeltä Zometa, jonka vaikuttava aine on tsoledronihappo, kaikkiin onkologisiin käyttötarkoituksiin asetuksen N:o 2309 93 nojalla. On 20 March 2001, Novartis obtained an MA under the centralised procedure for the medicinal product Zometa, the active substance of which is zoledronic acid, for a series of oncology indications, on the basis of Regulation No 2309/93. 14 Väliintulija Teva Pharma B. V. (jäljempänä Teva) haki 25. 5. 2011 asetuksen N:o 726 2004 4 artiklan 1 kohdan mukaista myyntilupaa lääkkeelle nimeltä Zoledronic acid Teva Pharmas-tsoledronihappo (jäljempänä Zoledronic acid Teva Pharma). 14 On 25 May 2011, the intervener, Teva Pharma BV (‘Teva') filed an application for marketing authorisation for the medicinal product Zoledronic acid Teva Pharma — zoledronic acid (‘Zoldedronic acid Teva Pharma'), pursuant to Article 4(1) of Regulation No 726/2004. Show more arrow right

Wiktionary

(chemistry, medicine) zoledronic acid Show more arrow right English zoledronic +‎ happo Show more arrow right

Wikipedia

Zoledronic acid Zoledronic acid, also known as zoledronate and sold under the brand name Zometa by Novartis among others, is a medication used to treat a number of bone diseases. These include osteoporosis, high blood calcium due to cancer, bone breakdown due to cancer, Paget's disease of bone and Duchenne muscular dystrophy (DMD). It is given by injection into a vein. Show more arrow right

-ni

-si

-nsa (singular)

Singular

Plural

Singular

Plural

Singular

Plural

Nom

-

tsoledronihapponi

tsoledronihapponi

tsoledronihapposi

tsoledronihapposi

tsoledronihapponsa

tsoledronihapponsa

Par

-ta

tsoledronihappoani

tsoledronihappojani

tsoledronihappoasi

tsoledronihappojasi

tsoledronihappoansa / tsoledronihappoaan

tsoledronihappojansa / tsoledronihappojaan

Gen

-n

tsoledronihapponi

tsoledronihappojeni

tsoledronihapposi

tsoledronihappojesi

tsoledronihapponsa

tsoledronihappojensa

Ill

mihin

tsoledronihappooni

tsoledronihappoihini

tsoledronihappoosi

tsoledronihappoihisi

tsoledronihappoonsa

tsoledronihappoihinsa

Ine

-ssa

tsoledronihapossani

tsoledronihapoissani

tsoledronihapossasi

tsoledronihapoissasi

tsoledronihapossansa / tsoledronihapossaan

tsoledronihapoissansa / tsoledronihapoissaan

Ela

-sta

tsoledronihapostani

tsoledronihapoistani

tsoledronihapostasi

tsoledronihapoistasi

tsoledronihapostansa / tsoledronihapostaan

tsoledronihapoistansa / tsoledronihapoistaan

All

-lle

tsoledronihapolleni

tsoledronihapoilleni

tsoledronihapollesi

tsoledronihapoillesi

tsoledronihapollensa / tsoledronihapolleen

tsoledronihapoillensa / tsoledronihapoillean

Ade

-lla

tsoledronihapollani

tsoledronihapoillani

tsoledronihapollasi

tsoledronihapoillasi

tsoledronihapollansa / tsoledronihapollaan

tsoledronihapoillansa / tsoledronihapoillaan

Abl

-lta

tsoledronihapoltani

tsoledronihapoiltani

tsoledronihapoltasi

tsoledronihapoiltasi

tsoledronihapoltansa / tsoledronihapoltaan

tsoledronihapoiltansa / tsoledronihapoiltaan

Tra

-ksi

tsoledronihapokseni

tsoledronihapoikseni

tsoledronihapoksesi

tsoledronihapoiksesi

tsoledronihapoksensa / tsoledronihapokseen

tsoledronihapoiksensa / tsoledronihapoikseen

Ess

-na

tsoledronihapponani

tsoledronihappoinani

tsoledronihapponasi

tsoledronihappoinasi

tsoledronihapponansa / tsoledronihapponaan

tsoledronihappoinansa / tsoledronihappoinaan

Abe

-tta

tsoledronihapottani

tsoledronihapoittani

tsoledronihapottasi

tsoledronihapoittasi

tsoledronihapottansa / tsoledronihapottaan

tsoledronihapoittansa / tsoledronihapoittaan

Com

-ne

-

tsoledronihappoineni

-

tsoledronihappoinesi

-

tsoledronihappoinensa / tsoledronihappoineen

Singular

Plural

Nom

-

tsoledronihapponi

tsoledronihapposi

tsoledronihapponsa

tsoledronihapponi

tsoledronihapposi

tsoledronihapponsa

Par

-ta

tsoledronihappoani

tsoledronihappoasi

tsoledronihappoansa / tsoledronihappoaan

tsoledronihappojani

tsoledronihappojasi

tsoledronihappojansa / tsoledronihappojaan

Gen

-n

tsoledronihapponi

tsoledronihapposi

tsoledronihapponsa

tsoledronihappojeni

tsoledronihappojesi

tsoledronihappojensa

Ill

mihin

tsoledronihappooni

tsoledronihappoosi

tsoledronihappoonsa

tsoledronihappoihini

tsoledronihappoihisi

tsoledronihappoihinsa

Ine

-ssa

tsoledronihapossani

tsoledronihapossasi

tsoledronihapossansa / tsoledronihapossaan

tsoledronihapoissani

tsoledronihapoissasi

tsoledronihapoissansa / tsoledronihapoissaan

Ela

-sta

tsoledronihapostani

tsoledronihapostasi

tsoledronihapostansa / tsoledronihapostaan

tsoledronihapoistani

tsoledronihapoistasi

tsoledronihapoistansa / tsoledronihapoistaan

All

-lle

tsoledronihapolleni

tsoledronihapollesi

tsoledronihapollensa / tsoledronihapolleen

tsoledronihapoilleni

tsoledronihapoillesi

tsoledronihapoillensa / tsoledronihapoillean

Ade

-lla

tsoledronihapollani

tsoledronihapollasi

tsoledronihapollansa / tsoledronihapollaan

tsoledronihapoillani

tsoledronihapoillasi

tsoledronihapoillansa / tsoledronihapoillaan

Abl

-lta

tsoledronihapoltani

tsoledronihapoltasi

tsoledronihapoltansa / tsoledronihapoltaan

tsoledronihapoiltani

tsoledronihapoiltasi

tsoledronihapoiltansa / tsoledronihapoiltaan

Tra

-ksi

tsoledronihapokseni

tsoledronihapoksesi

tsoledronihapoksensa / tsoledronihapokseen

tsoledronihapoikseni

tsoledronihapoiksesi

tsoledronihapoiksensa / tsoledronihapoikseen

Ess

-na

tsoledronihapponani

tsoledronihapponasi

tsoledronihapponansa / tsoledronihapponaan

tsoledronihappoinani

tsoledronihappoinasi

tsoledronihappoinansa / tsoledronihappoinaan

Abe

-tta

tsoledronihapottani

tsoledronihapottasi

tsoledronihapottansa / tsoledronihapottaan

tsoledronihapoittani

tsoledronihapoittasi

tsoledronihapoittansa / tsoledronihapoittaan

Com

-ne

-

-

-

tsoledronihappoineni

tsoledronihappoinesi

tsoledronihappoinensa / tsoledronihappoineen

-mme

-nne

-nsa (plural)

Singular

Plural

Singular

Plural

Singular

Plural

Nom

-

tsoledronihappomme

tsoledronihappomme

tsoledronihapponne

tsoledronihapponne

tsoledronihapponsa

tsoledronihapponsa

Par

-ta

tsoledronihappoamme

tsoledronihappojamme

tsoledronihappoanne

tsoledronihappojanne

tsoledronihappoansa / tsoledronihappoaan

tsoledronihappojansa / tsoledronihappojaan

Gen

-n

tsoledronihappomme

tsoledronihappojemme

tsoledronihapponne

tsoledronihappojenne

tsoledronihapponsa

tsoledronihappojensa

Ill

mihin

tsoledronihappoomme

tsoledronihappoihimme

tsoledronihappoonne

tsoledronihappoihinne

tsoledronihappoonsa

tsoledronihappoihinsa

Ine

-ssa

tsoledronihapossamme

tsoledronihapoissamme

tsoledronihapossanne

tsoledronihapoissanne

tsoledronihapossansa / tsoledronihapossaan

tsoledronihapoissansa / tsoledronihapoissaan

Ela

-sta

tsoledronihapostamme

tsoledronihapoistamme

tsoledronihapostanne

tsoledronihapoistanne

tsoledronihapostansa / tsoledronihapostaan

tsoledronihapoistansa / tsoledronihapoistaan

All

-lle

tsoledronihapollemme

tsoledronihapoillemme

tsoledronihapollenne

tsoledronihapoillenne

tsoledronihapollensa / tsoledronihapolleen

tsoledronihapoillensa / tsoledronihapoillean

Ade

-lla

tsoledronihapollamme

tsoledronihapoillamme

tsoledronihapollanne

tsoledronihapoillanne

tsoledronihapollansa / tsoledronihapollaan

tsoledronihapoillansa / tsoledronihapoillaan

Abl

-lta

tsoledronihapoltamme

tsoledronihapoiltamme

tsoledronihapoltanne

tsoledronihapoiltanne

tsoledronihapoltansa / tsoledronihapoltaan

tsoledronihapoiltansa / tsoledronihapoiltaan

Tra

-ksi

tsoledronihapoksemme

tsoledronihapoiksemme

tsoledronihapoksenne

tsoledronihapoiksenne

tsoledronihapoksensa / tsoledronihapokseen

tsoledronihapoiksensa / tsoledronihapoikseen

Ess

-na

tsoledronihapponamme

tsoledronihappoinamme

tsoledronihapponanne

tsoledronihappoinanne

tsoledronihapponansa / tsoledronihapponaan

tsoledronihappoinansa / tsoledronihappoinaan

Abe

-tta

tsoledronihapottamme

tsoledronihapoittamme

tsoledronihapottanne

tsoledronihapoittanne

tsoledronihapottansa / tsoledronihapottaan

tsoledronihapoittansa / tsoledronihapoittaan

Com

-ne

-

tsoledronihappoinemme

-

tsoledronihappoinenne

-

tsoledronihappoinensa / tsoledronihappoineen

Singular

Plural

Nom

-

tsoledronihappomme

tsoledronihapponne

tsoledronihapponsa

tsoledronihappomme

tsoledronihapponne

tsoledronihapponsa

Par

-ta

tsoledronihappoamme

tsoledronihappoanne

tsoledronihappoansa / tsoledronihappoaan

tsoledronihappojamme

tsoledronihappojanne

tsoledronihappojansa / tsoledronihappojaan

Gen

-n

tsoledronihappomme

tsoledronihapponne

tsoledronihapponsa

tsoledronihappojemme

tsoledronihappojenne

tsoledronihappojensa

Ill

mihin

tsoledronihappoomme

tsoledronihappoonne

tsoledronihappoonsa

tsoledronihappoihimme

tsoledronihappoihinne

tsoledronihappoihinsa

Ine

-ssa

tsoledronihapossamme

tsoledronihapossanne

tsoledronihapossansa / tsoledronihapossaan

tsoledronihapoissamme

tsoledronihapoissanne

tsoledronihapoissansa / tsoledronihapoissaan

Ela

-sta

tsoledronihapostamme

tsoledronihapostanne

tsoledronihapostansa / tsoledronihapostaan

tsoledronihapoistamme

tsoledronihapoistanne

tsoledronihapoistansa / tsoledronihapoistaan

All

-lle

tsoledronihapollemme

tsoledronihapollenne

tsoledronihapollensa / tsoledronihapolleen

tsoledronihapoillemme

tsoledronihapoillenne

tsoledronihapoillensa / tsoledronihapoillean

Ade

-lla

tsoledronihapollamme

tsoledronihapollanne

tsoledronihapollansa / tsoledronihapollaan

tsoledronihapoillamme

tsoledronihapoillanne

tsoledronihapoillansa / tsoledronihapoillaan

Abl

-lta

tsoledronihapoltamme

tsoledronihapoltanne

tsoledronihapoltansa / tsoledronihapoltaan

tsoledronihapoiltamme

tsoledronihapoiltanne

tsoledronihapoiltansa / tsoledronihapoiltaan

Tra

-ksi

tsoledronihapoksemme

tsoledronihapoksenne

tsoledronihapoksensa / tsoledronihapokseen

tsoledronihapoiksemme

tsoledronihapoiksenne

tsoledronihapoiksensa / tsoledronihapoikseen

Ess

-na

tsoledronihapponamme

tsoledronihapponanne

tsoledronihapponansa / tsoledronihapponaan

tsoledronihappoinamme

tsoledronihappoinanne

tsoledronihappoinansa / tsoledronihappoinaan

Abe

-tta

tsoledronihapottamme

tsoledronihapottanne

tsoledronihapottansa / tsoledronihapottaan

tsoledronihapoittamme

tsoledronihapoittanne

tsoledronihapoittansa / tsoledronihapoittaan

Com

-ne

-

-

-

tsoledronihappoinemme

tsoledronihappoinenne

tsoledronihappoinensa / tsoledronihappoineen

 Create new exercises Report an issue Exercises Solved!

Singular

Plural

Nom

-

tsoledronihappo

tsoledronihapot

Par

-ta

 Solve

Gen

-n

tsoledronihapon

 Solve

Ill

mihin

tsoledronihappoihin

 Solve

Ine

-ssa

tsoledronihapossa

 Solve

Ela

-sta

tsoledronihaposta

tsoledronihapoista

All

-lle

tsoledronihapoille

 Solve

Ade

-lla

tsoledronihapolla

tsoledronihapoilla

Abl

-lta

tsoledronihapolta

tsoledronihapoilta

Tra

-ksi

tsoledronihapoksi

 Solve

Ess

-na

tsoledronihappona

tsoledronihappoina

Abe

-tta

tsoledronihapotta

tsoledronihapoitta

Com

-ne

-

tsoledronihappoine

Ins

-in

-

tsoledronihapoin

Declensions

Singular

Plural

Nom

-

tsoledronihappo

tsoledronihapot

Par

-ta

Gen

-n

tsoledronihapon

Ill

mihin

tsoledronihappoihin

Ine

-ssa

tsoledronihapossa

Ela

-sta

tsoledronihaposta

tsoledronihapoista

All

-lle

tsoledronihapoille

Ade

-lla

tsoledronihapolla

tsoledronihapoilla

Abl

-lta

tsoledronihapolta

tsoledronihapoilta

Tra

-ksi

tsoledronihapoksi

Ess

-na

tsoledronihappona

tsoledronihappoina

Abe

-tta

tsoledronihapotta

tsoledronihapoitta

Com

-ne

-

tsoledronihappoine

Ins

-in

-

tsoledronihapoin
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